Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 8/20 | 0.64 |
| ▸ | NPC1 | O15118 | 7/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14288613 | 0.95 | RAB9A (0.70) | HTR1AHRH3RAB9ANPC1L3MBTL1 | |
| Dimethylamine SCHEMBL7961651 | 0.91 | ALDH1A1 (0.61) | HTR1AHRH3RAB9ANPC1L3MBTL1 | |
| Dimethylamine SCHEMBL7947230 | 0.87 | NOTUM (0.62) | HTR1AHRH3RAB9ANPC1L3MBTL1 | |
| SCHEMBL91541 | 0.81 | NOTUM (0.68) | HTR1AHRH3RAB9ANPC1L3MBTL1 | |
| SCHEMBL16975850 | 0.80 | SMN1; SMN2 (0.71) | RAB9ANPC1L3MBTL1SMN1; SMN2HTT | |
| SCHEMBL5795375 | 0.80 | SMN1; SMN2 (0.69) | HTR1AHRH3RAB9ANPC1L3MBTL1 | |
| SCHEMBL10914161 | 0.79 | RAB9A (0.69) | HTR1AHRH3RAB9ANPC1L3MBTL1 | |
| SCHEMBL19131259 | 0.78 | SMN1; SMN2 (0.64) | HTR1AHRH3RAB9ANPC1CYP1A2 | |
| SCHEMBL12396054 | 0.78 | PPARA (0.82) | HRH3RAB9ANPC1L3MBTL1CYP1A2 | |
| Oxolamine SCHEMBL893333 | 0.78 | HTR1A (1.00) | HTR1AHRH3RAB9ANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277872-B1 | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-08-21 | — | — | US | disclosed |