Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5795781 | 0.86 | PTGS2 (0.38) | PTGS2MAOA | |
| SCHEMBL5795645 | 0.77 | TAS1R3 (0.48) | PTGS2TAS1R3TAS1R1MAOASLC6A2 | |
| SCHEMBL5795647 | 0.77 | TAS1R3 (0.48) | PTGS2TAS1R3TAS1R1MAOASLC6A2 | |
| SCHEMBL7214901 | 0.73 | PTGS2 (0.45) | PTGS2TAS1R3TAS1R1MAOASLC6A2 | |
| SCHEMBL10631836 | 0.69 | PTGS2 (0.47) | PTGS2TAS1R3TAS1R1MAOASLC6A2 | |
| SCHEMBL2307317 | 0.66 | SLC6A2 (0.53) | PTGS2SLC6A2SLC6A4SLC6A3NR3C1 | |
| SCHEMBL30795530 | 0.65 | PTGS2 (0.49) | PTGS2MAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15324491 | 0.64 | MAOA (0.42) | PTGS2TAS1R3TAS1R1MAOASLC6A2 | |
| SCHEMBL3106353 | 0.64 | TUBB4A (0.51) | TAS1R3TAS1R1MAOACTNNB1WNT3A | |
| Hydrochloric Acid SCHEMBL16583860 | 0.64 | MAOA (0.42) | PTGS2TAS1R3TAS1R1MAOASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006034480-A2 | SULFONAMIDE BICYCLIC COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-03-30 | — | — | WO | disclosed |