Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | SPR | P35270 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2139709 | 0.86 | ALDH1A1 (0.41) | CYP3A4ALDH1A1CYP2C9CYP2C19CA12 | |
| SCHEMBL6215165 | 0.86 | ALDH1A1 (0.41) | CYP3A4ALDH1A1CYP2C9CYP2C19CA12 | |
| SCHEMBL12621536 | 0.85 | SPR (0.41) | NQO2CA12CA1CA7CA14 | |
| SCHEMBL3627157 | 0.84 | CTSB (0.51) | CYP3A4ALDH1A1CYP2C9CYP2C19CA12 | |
| SCHEMBL3619339 | 0.83 | CYP2C19 (0.45) | CYP3A4ALDH1A1CYP2C9CYP2C19CA12 | |
| SCHEMBL2139009 | 0.83 | MRGPRX4 (0.46) | CYP3A4ALDH1A1CYP2C9CYP2C19PKM | |
| SCHEMBL14266632 | 0.83 | ALDH1A1 (0.58) | OPRM1OPRD1OPRK1CYP3A4ALDH1A1 | |
| SCHEMBL3625060 | 0.82 | SLC7A5 (0.47) | CYP3A4ALDH1A1CYP2C9CYP2C19CA12 | |
| SCHEMBL2141158 | 0.82 | LOXL2 (0.54) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL3627164 | 0.81 | CYP3A4 (0.47) | CYP3A4ALDH1A1CYP2C9CYP2C19CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1631562-A1 | CHROMENE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | Pharmacia Corporation (US) | 2006-03-08 | — | — | EP | disclosed |
| EP-1615905-A2 | BENZOPYRAN COMPOUNDS USEFUL FOR TREATING INFLAMMATORY CONDITIONS | Pharmacia Corporation (US) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004087687-A1 | CHROMENE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | PHARMACIA CORPORATION (US) | 2004-10-14 | — | — | WO | disclosed |
| WO-2004087686-A2 | BENZOPYRAN COMPOUNDS USEFUL FOR TREATING INFLAMMATORY CONDITIONS | PHARMACIA CORPORATION (US) | 2004-10-14 | — | — | WO | disclosed |