Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562892 | 0.83 | HTR1A (0.41) | HTR2AHPGDSMN1; SMN2DRD2ALOX15 | |
| SCHEMBL7698397 | 0.78 | PDCD1 (0.44) | BCL2L1HPGDKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL982140 | 0.78 | GABRA1 (0.35) | HPGDSMN1; SMN2KMT2A | |
| SCHEMBL7703138 | 0.78 | ALDH1A1 (0.34) | TRPA1ALDH1A1TSHR | |
| SCHEMBL721135 | 0.76 | CALM1 (0.44) | HTR2ACALM1BCL2BCL2L1ALOX5 | |
| SCHEMBL983255 | 0.76 | SREBF2 (0.33) | HPGDSMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL3126217 | 0.74 | HTR2A (0.42) | HTR2ACALM1BCL2BCL2L1ALOX5 | |
| SCHEMBL2410994 | 0.74 | HTR2A (0.42) | HTR2ACALM1BCL2BCL2L1ALOX5 | |
| SCHEMBL3395146 | 0.74 | BCL2 (0.50) | HTR2ACALM1BCL2BCL2L1PTPN1 | |
| SCHEMBL7463754 | 0.74 | HTR2A (0.42) | HTR2ACALM1BCL2BCL2L1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006033995-A2 | THIAZOLIDIN-4-ONES HAVING ANTI-HEPATITIS B ACTIVITY | VALEANT RESEARCH AND DEVELOPMENT (US) | 2006-03-30 | — | — | WO | disclosed |