Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796310 | 1.00 | OPRD1 (0.44) | OPRD1OPRM1OPRK1OPRL1ADAM17 | |
| SCHEMBL4881637 | 0.82 | OPRD1 (0.45) | OPRD1OPRM1OPRK1OPRL1ADAM17 | |
| SCHEMBL4873590 | 0.82 | OPRD1 (0.45) | OPRD1OPRM1OPRK1OPRL1ADAM17 | |
| SCHEMBL4873596 | 0.82 | OPRD1 (0.45) | OPRD1OPRM1OPRK1OPRL1ADAM17 | |
| SCHEMBL27736564 | 0.81 | ADAM17 (0.56) | OPRD1OPRM1OPRK1OPRL1ADAM17 | |
| SCHEMBL4868377 | 0.80 | ADAM17 (0.48) | OPRD1ADAM17ALDH1A1MEN1KMT2A | |
| SCHEMBL4882566 | 0.80 | HDAC4 (0.48) | OPRD1OPRM1OPRK1OPRL1ADAM17 | |
| SCHEMBL4872683 | 0.79 | ADAM17 (0.52) | OPRM1ADAM17ALDH1A1MEN1KMT2A | |
| SCHEMBL5476317 | 0.78 | OPRM1 (0.69) | OPRD1OPRM1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL2846322 | 0.76 | ADAM17 (0.53) | OPRD1OPRM1OPRK1ADAM17ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1736467-A1 | NOVEL SULFONAMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-12-27 | — | — | EP | disclosed |