Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flavanone SCHEMBL5796766 | 0.80 | AR (0.68) | ARCYP3A4CYP19A1MAOBMAOA | |
| SCHEMBL126600 | 0.78 | AR (0.52) | ARCYP3A4CYP19A1MAOBMAOA | |
| SCHEMBL130268 | 0.76 | CYP19A1 (0.49) | ARCYP3A4CYP19A1MAOBMAOA | |
| SCHEMBL13730471 | 0.76 | CYP19A1 (0.49) | ARCYP3A4CYP19A1MAOBMAOA | |
| SCHEMBL2283832 | 0.76 | CYP3A4 (0.49) | ARCYP3A4CYP19A1MAOBMAOA | |
| SCHEMBL19746 | 0.76 | CYP19A1 (0.45) | ARCYP19A1MAOBMAOARAB9A | |
| SCHEMBL5088610 | 0.75 | CYP19A1 (0.47) | ARCYP3A4CYP19A1MAOBMAOA | |
| Methane SCHEMBL27973705 | 0.74 | CYP19A1 (0.44) | ARCYP19A1MAOBMAOARAB9A | |
| SCHEMBL11733122 | 0.74 | CYP19A1 (0.44) | ARCYP19A1MAOBMAOARAB9A | |
| SCHEMBL5313705 | 0.73 | DNMT3B (0.57) | ARCYP3A4CYP19A1MAOBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030322-A2 | USE OF FLA VONE/FLA VANONE DERIVATIVES FN THE TREATMENT OR PREVENTION OF RESPIRATORY CONDITIONS | UNIVERSITY OF MANITOBA (CA) | 2006-03-23 | — | — | WO | disclosed |