Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.61 |
| ▸ | MAOB | P27338 | 5/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | YES1 | P07947 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362227 | 0.82 | AR (1.00) | ARADORA3CYP3A4NPC1RAB9A | |
| SCHEMBL126598 | 0.82 | AR (1.00) | ARADORA3CYP3A4NPC1RAB9A | |
| SCHEMBL5796768 | 0.80 | AR (0.46) | ARADORA3CYP3A4NPC1RAB9A | |
| Liquirtigenin SCHEMBL3120177 | 0.79 | MAOB (0.87) | ARADORA3CYP3A4NPC1RAB9A | |
| 4'-Hydroxy-Flavanone SCHEMBL10362253 | 0.78 | ADORA3 (1.00) | ARADORA3CYP3A4NPC1RAB9A | |
| 4'-Hydroxy-Flavanone SCHEMBL2283830 | 0.78 | ADORA3 (1.00) | ARADORA3CYP3A4NPC1RAB9A | |
| 4'-Hydroxy-Flavanone SCHEMBL2283823 | 0.78 | ADORA3 (1.00) | ARADORA3CYP3A4NPC1RAB9A | |
| Flavanone SCHEMBL27595693 | 0.78 | ADORA3 (0.88) | ARADORA3CYP3A4NPC1RAB9A | |
| SCHEMBL5313705 | 0.78 | DNMT3B (0.57) | ARADORA3CYP3A4NPC1RAB9A | |
| 7-Hydroxyflavanone SCHEMBL130266 | 0.77 | MAOB (1.00) | ARADORA3CYP3A4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030322-A2 | USE OF FLA VONE/FLA VANONE DERIVATIVES FN THE TREATMENT OR PREVENTION OF RESPIRATORY CONDITIONS | UNIVERSITY OF MANITOBA (CA) | 2006-03-23 | — | — | WO | disclosed |