Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799613 | 0.88 | HDAC1 (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5799119 | 0.88 | RAB9A (0.58) | MAPTRAB9AKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5796649 | 0.86 | TDP1 (0.42) | KMT2AKDM4EPOLBMEN1TDP1 | |
| SCHEMBL5795757 | 0.86 | POLB (0.49) | MAPTKMT2ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL5799558 | 0.83 | ALDH1A1 (0.63) | MAPTRAB9AKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5797755 | 0.83 | KMT2A (0.46) | MAPTRAB9AKMT2AKDM4EPOLB | |
| Alcohol SCHEMBL6156323 | 0.76 | SMN1; SMN2 (0.58) | MAPTRAB9AKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5799597 | 0.76 | NPC1 (0.50) | MAPTRAB9AKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5796100 | 0.76 | RAB9A (0.55) | MAPTRAB9AKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5797374 | 0.76 | HDAC6 (0.59) | MAPTRAB9AKMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |