Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796100 | 0.90 | RAB9A (0.55) | POLBRECQLKDM4EALDH1A1MAPT | |
| SCHEMBL5811205 | 0.89 | HDAC1 (0.53) | SRD5A2RECQLPGR | |
| SCHEMBL5796774 | 0.86 | MAPT (0.48) | POLBKDM4ETDP1ALDH1A1MAPT | |
| SCHEMBL5799558 | 0.82 | ALDH1A1 (0.63) | POLBKDM4ETDP1ALDH1A1MAPT | |
| SCHEMBL5799597 | 0.81 | NPC1 (0.50) | KDM4ETDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL5797755 | 0.80 | KMT2A (0.46) | POLBKDM4ETDP1ALDH1A1MAPT | |
| SCHEMBL5812423 | 0.78 | FFAR1 (0.56) | SRD5A2TDP1MEN1KMT2APKM | |
| SCHEMBL5799119 | 0.78 | RAB9A (0.58) | POLBKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL11527582 | 0.76 | HPGD (0.50) | POLBRECQLKDM4EALDH1A1MAPT | |
| SCHEMBL5796649 | 0.76 | TDP1 (0.42) | POLBKDM4ETDP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |