Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.68 |
| ▸ | HPGD | P15428 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | APEX1 | P27695 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.65 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29993383 | 0.88 | ABCG2 (1.00) | ABCG2CYP3A4ALDH1A1HSD17B10HPGD | |
| SCHEMBL253523 | 0.88 | ABCG2 (1.00) | ABCG2CYP3A4ALDH1A1HSD17B10HPGD | |
| SCHEMBL4650702 | 0.87 | ABCG2 (1.00) | ABCG2CYP3A4ALDH1A1HSD17B10HPGD | |
| SCHEMBL7162949 | 0.85 | KDM4E (0.74) | ABCG2CYP3A4ALDH1A1HSD17B10HPGD | |
| SCHEMBL3282447 | 0.85 | KDM4E (0.71) | ABCG2CYP3A4ALDH1A1HSD17B10HPGD | |
| SCHEMBL12313777 | 0.83 | ALDH1A1 (0.65) | ABCG2CYP3A4ALDH1A1HSD17B10HPGD | |
| SCHEMBL311968 | 0.82 | CYP3A4 (0.72) | ABCG2CYP3A4ALDH1A1HSD17B10HPGD | |
| SCHEMBL12266094 | 0.82 | ALDH1A1 (0.63) | ABCG2CYP3A4ALDH1A1HSD17B10HPGD | |
| SCHEMBL311942 | 0.82 | ALDH1A1 (0.63) | ABCG2CYP3A4ALDH1A1HSD17B10HPGD | |
| SCHEMBL345696 | 0.81 | MEN1 (1.00) | CYP3A4ALDH1A1HSD17B10HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-212757256-U | Be applied to drying device that buchanania chinensis draws flavonoid composition | 赣南卫生健康职业学院 | 2021-03-23 | — | — | CN | disclosed |
| WO-2006030322-A2 | USE OF FLA VONE/FLA VANONE DERIVATIVES FN THE TREATMENT OR PREVENTION OF RESPIRATORY CONDITIONS | UNIVERSITY OF MANITOBA (CA) | 2006-03-23 | — | — | WO | disclosed |
| EP-0233105-A1 | Therapeutical compositions based on 3-alkoxyflavone derivatives and derivatives of 3-alkoxyflavones | INSTITUT PASTEUR (FR) | 1987-08-19 | — | — | EP | disclosed |