Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | RECQL | P46063 | 2/20 | 0.71 |
| ▸ | TP53 | P04637 | 2/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.71 |
| ▸ | CDK2 | P24941 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.70 |
| ▸ | MMP1 | P03956 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14259678 | 0.88 | TUBB4A (0.74) | KDM4EHSD17B10MEN1MAPTKMT2A | |
| SCHEMBL29512814 | 0.87 | KDM4E (0.73) | KDM4EHSD17B10MEN1MAPTKMT2A | |
| SCHEMBL34716 | 0.87 | KDM4E (0.73) | KDM4EHSD17B10MEN1MAPTKMT2A | |
| SCHEMBL16882942 | 0.86 | KDM4E (0.68) | KDM4EHSD17B10MEN1MAPTKMT2A | |
| SCHEMBL4165696 | 0.85 | MAPT (0.64) | KDM4EHSD17B10MEN1MAPTKMT2A | |
| SCHEMBL5796864 | 0.85 | ABCG2 (0.78) | KDM4EHSD17B10MEN1MAPTKMT2A | |
| SCHEMBL12266079 | 0.83 | MAPT (0.59) | KDM4EHSD17B10MEN1MAPTKMT2A | |
| SCHEMBL13840378 | 0.83 | ABCG2 (0.65) | KDM4EHSD17B10MEN1MAPTKMT2A | |
| SCHEMBL29149071 | 0.83 | ABCG2 (0.63) | KDM4EHSD17B10MEN1MAPTKMT2A | |
| SCHEMBL4165699 | 0.83 | POLH (0.71) | KDM4EHSD17B10MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) | 2009-05-21 | — | — | US | claimed |
| US-7709223-B2 | Method for detecting bacteria with chromogenic substrates for β-D-ribofuranosidase | BURTON MICHAEL | 2010-05-04 | — | — | US | disclosed |
| US-7531646-B2 | β-D-ribosidase activity indicators with a chromogenic substrate | BURTON MICHAEL | 2009-05-12 | — | — | US | disclosed |
| US-7531646-B2 | β-D-ribosidase activity indicators with a chromogenic substrate | BURTON MICHAEL | 2009-05-12 | — | — | US | disclosed |
| US-20080193959-A1 | Enzyme Substrates | BURTON MICHAEL | 2008-08-14 | — | — | US | disclosed |
| US-7384763-B2 | Method of detecting β-D-ribofuranosidase activity | BURTON MICHAEL | 2008-06-10 | — | — | US | disclosed |
| EP-1438423-B1 | ENZYME ACTIVITY INDICATORS | BURTON MICHAEL (GB) | 2007-12-12 | — | — | EP | disclosed |
| EP-1438424-B1 | ENZYME SUBSTRATES FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY | BURTON MICHAEL (GB) | 2006-01-18 | — | — | EP | disclosed |
| US-20040259181-A1 | detecting beta-D-ribofuranosidase activity using novel chromogenic beta-D-ribofuranoside substrates such as catechol-beta-D-ribofuranoside or 3',4'-dihydroxyflavone-4'-beta-D-dibofuranoside; kits | BURTON MICHAEL (GB) | 2004-12-23 | — | — | US | disclosed |
| US-20040235081-A1 | Enzyme activity indicators | BURTON MICHAEL (GB) | 2004-11-25 | — | — | US | disclosed |
| EP-1438423-A1 | ENZYME ACTIVITY INDICATORS | Burton, Michael (GB) | 2004-07-21 | — | — | EP | disclosed |
| EP-1438424-A2 | ENZYME SUBSTRATES FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY | Burton, Michael (GB) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003035900-A1 | ENZYME ACTIVITY INDICATORS | BURTON MICHAEL (GB) | 2003-05-01 | — | — | WO | disclosed |
| WO-2003035897-A2 | ENZYME SUBSTRATES FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY | BURTON MICHAEL (GB) | 2003-05-01 | — | — | WO | disclosed |
| US-20020147353-A1 | Novel flavonoids | VERENIGING CHRISTELIJK WETENSCHAPPELIJK ANDERWIJS (NL) | 2002-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147353-A1 | Novel flavonoids | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1, ABCC8 | KDM4E 3228/4885HSD17B10 892/4885MEN1 2151/4885 |
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | CAT, NQO1, GPX4 | KDM4E 4144/4885HSD17B10 1555/4885MEN1 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.