Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 11/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.68 |
| ▸ | CNR1 | P21554 | 1/20 | 0.68 |
| ▸ | ACHE | P22303 | 1/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.68 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.68 |
| ▸ | MC3R | P41968 | 1/20 | 0.68 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.68 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.68 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.68 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24400362 | 0.87 | ADORA2B (0.51) | ADORA2BPOLBPIK3CDADORA3CNR1 | |
| Caffeine SCHEMBL29549294 | 0.81 | ADORA2B (1.00) | ADORA2BPOLBPIK3CDADORA3CNR1 | |
| Caffeine SCHEMBL29549224 | 0.81 | ADORA2B (1.00) | ADORA2BPOLBPIK3CDADORA3CNR1 | |
| Caffeine SCHEMBL10478364 | 0.81 | ADORA2B (1.00) | ADORA2BPOLBPIK3CDADORA3CNR1 | |
| Caffeine SCHEMBL8569482 | 0.81 | ADORA2B (1.00) | ADORA2BPOLBPIK3CDADORA3CNR1 | |
| SCHEMBL11698769 | 0.81 | ADORA2B (0.72) | ADORA2BPOLBPIK3CDADORA3CNR1 | |
| Caffeine SCHEMBL901194 | 0.81 | ADORA2B (1.00) | ADORA2BPOLBPIK3CDADORA3CNR1 | |
| Caffeine SCHEMBL29590919 | 0.81 | ADORA2B (1.00) | ADORA2BPOLBPIK3CDADORA3CNR1 | |
| Caffeine SCHEMBL5671 | 0.81 | ADORA2B (1.00) | ADORA2BPOLBPIK3CDADORA3CNR1 | |
| Caffeine SCHEMBL6694833 | 0.80 | ADORA2B (0.89) | ADORA2BPOLBPIK3CDADORA3CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11541006-B2 | Aqueous formulation for insoluble drugs | Chen, Andrew Xian (US) | 2023-01-03 | — | — | US | claimed |
| CN-113993524-A | Use of lipid compounds for preventing or treating diabetes | 中国医学科学院基础医学研究所 | 2022-01-28 | — | — | CN | claimed |
| WO-2022008134-A1 | TREATMENT OF SEASONAL HAIR THINNING | DR. KURT WOLFF GMBH & CO. KG (DE) | 2022-01-13 | — | — | WO | claimed |
| EP-3936110-A1 | TREATMENT OF SEASONAL HAIR THINNING | Dr. Kurt Wolff GmbH & Co. KG (DE) | 2022-01-12 | — | — | EP | claimed |
| EP-3761961-A1 | AQUEOUS FORMULATIONS FOR INSOLUBLE DRUGS | Chen, Andrew Xian (US) | 2021-01-13 | — | — | EP | claimed |
| US-20200368159-A1 | AQUEOUS FORMULATION FOR INSOLUBLE DRUGS | Chen, Andrew Xian (US) | 2020-11-26 | — | — | US | claimed |
| WO-2019173526-A1 | AQUEOUS FORMULATIONS FOR INSOLUBLE DRUGS | CHEN ANDREW XIAN (US) | 2019-09-12 | — | — | WO | claimed |
| US-20110118464-A1 | HALOGENATED XANTHINE DERIVATIVES AND PRECURSORS THEREOF FOR ANTI-CANCER AND ANTI-METASTASIS ACTIVITY AND PREPARING METHOD THEREOF | KAOHSIUNG MEDICAL UNIVERSITY | 2011-05-19 | — | — | US | claimed |
| US-20250313564-A1 | ACIDIC SALT OR CRYSTAL FORM OF NITROGEN-CONTAINING FUSED RING DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) | 2025-10-09 | — | — | US | disclosed |
| CN-113072546-B | Five-membered heteroaromatic derivative and preparation method and application thereof | 广东东阳光药业股份有限公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-115368264-B | Compounds, liposomes and uses thereof | 北京理工大学 | 2025-03-07 | — | — | CN | disclosed |
| CN-116217575-B | Preparation method of 8-bromine theophylline | 广东赛烽医药科技有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-119255997-A | Modulators of c-MYC mRNA translation and their use in the treatment of cancer | 艾尼莫生物科技公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-119233976-A | Modulators of c-MYC mRNA translation and their use in the treatment of cancer | 艾尼莫生物科技公司 | 2024-12-31 | — | — | CN | disclosed |
| US-5096716-A | Dosage form for administering calcium antagonist nicardipine | ALZA CORPORATION (US) | 1992-03-17 | — | — | US | disclosed |
| EP-0250083-B1 | DOSAGE FORM WITH MEANS FOR GOVERNING RATE OF GAS FORMATION | ALZA CORPORATION (US) | 1991-12-04 | — | — | EP | disclosed |
| EP-0455648-A1 | DOSAGE FORM FOR ADMINISTERING CALCIUM ANTAGONIST. | ALZA CORP (US) | 1991-11-13 | — | — | EP | disclosed |
| WO-1990008536-A1 | DOSAGE FORM FOR ADMINISTERING CALCIUM ANTAGONIST | ALZA CORPORATION (US) | 1990-08-09 | — | — | WO | disclosed |
| US-4847093-A | Dosage form with means for governing rate of gas formation | ALZA CORPORATION (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0250083-A2 | Dosage form with means for governing rate of gas formation | ALZA CORPORATION (US) | 1987-12-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250313564-A1 | ACIDIC SALT OR CRYSTAL FORM OF NITROGEN-CONTAINING FUSED RING DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | NR5A1, HSD17B11, CYP17A1 | ADORA2B 4168/4885POLB 4434/4885PIK3CD 2699/4885 |
| US-20110118464-A1 | HALOGENATED XANTHINE DERIVATIVES AND PRECURSORS THEREOF FOR ANTI-CANCER AND ANTI-METASTASIS ACTIVITY AND PREPARING METHOD THEREOF | TK1, XDH, KYAT1 | ADORA2B 2865/4885POLB 554/4885PIK3CD 4494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.