Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798239 | 1.00 | POLB (0.41) | POLBNPSR1ALDH1A1MAPTMMP8 | |
| SCHEMBL5801089 | 1.00 | POLB (0.41) | POLBNPSR1ALDH1A1MAPTMMP8 | |
| SCHEMBL5885245 | 0.76 | ALDH1A1 (0.50) | POLBNPSR1ALDH1A1MAPTMMP8 | |
| SCHEMBL7065146 | 0.76 | MMP8 (0.51) | POLBNPSR1ALDH1A1MAPTMMP8 | |
| SCHEMBL5798028 | 0.74 | KMT2A (0.43) | ALDH1A1MAPTMMP8PIN1NPC1 | |
| SCHEMBL5799304 | 0.74 | KMT2A (0.43) | ALDH1A1MAPTMMP8PIN1NPC1 | |
| SCHEMBL23657388 | 0.72 | POLB (0.56) | POLBNPSR1ALDH1A1MAPTMMP8 | |
| SCHEMBL23738123 | 0.71 | POLB (0.45) | POLBNPSR1ALDH1A1MAPTMMP8 | |
| SCHEMBL23718650 | 0.69 | POLB (0.43) | POLBNPSR1ALDH1A1MAPTMMP8 | |
| SCHEMBL5798332 | 0.69 | NPC1 (0.40) | ALDH1A1MAPTMMP8PIN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030208-A1 | AMINO ACID | UNIVERSITY OF LEEDS (GB) | 2006-03-23 | — | — | WO | claimed |