Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | CTSG | P08311 | 2/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.36 |
| ▸ | CMA1 | P23946 | 2/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5801196 | 1.00 | NPC1 (0.40) | NPC1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5799304 | 0.79 | KMT2A (0.43) | NPC1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5798028 | 0.79 | KMT2A (0.43) | NPC1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5801142 | 0.74 | CYP26A1 (0.40) | NPC1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5800376 | 0.74 | CYP26A1 (0.40) | NPC1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5821075 | 0.74 | ALDH1A1 (0.38) | NPC1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL16840480 | 0.72 | AAK1 (0.41) | NPC1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL16843138 | 0.72 | AAK1 (0.44) | NPC1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL13337442 | 0.72 | AAK1 (0.44) | NPC1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5800166 | 0.72 | TSHR (0.44) | NPC1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030208-A1 | AMINO ACID | UNIVERSITY OF LEEDS (GB) | 2006-03-23 | — | — | WO | claimed |