SCHEMBL5797162

SCHEMBL5797162

CC1(C)C[C@H]2C3=CC[C@@H]4[C@@]5(C)C[C@H](O)[C@H](O)C(C)(C)[C@@H]5CC[C@@]4(C)[C@]3(C)C[C@H](O)[C@@]2(C(=O)O)C[C@@H]1O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ F3 P13726 3/20 0.66
▸ SIRT5 Q9NXA8 3/20 0.66
▸ CYP3A4 P08684 1/20 0.66
▸ MAPK1 P28482 1/20 0.66
▸ OXTR P30559 1/20 0.66
▸ AVPR1A P37288 1/20 0.66
▸ CD81 P60033 1/20 0.66
▸ PTPN1 P18031 8/20 0.63
▸ PTPN2 P17706 5/20 0.63
▸ GPBAR1 Q8TDU6 4/20 0.63
▸ AKR1B10 O60218 3/20 0.63
▸ PYGM P11217 2/20 0.63
▸ AKR1B1 P15121 1/20 0.63
▸ POLB P06746 4/20 0.55
▸ PTPN6 P29350 3/20 0.55
▸ USP7 Q93009 3/20 0.55
▸ EGLN2 Q96KS0 1/20 0.55
▸ EGLN1 Q9GZT9 1/20 0.55
▸ EGLN3 Q9H6Z9 1/20 0.55
▸ P4HTM Q9NXG6 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5797167 1.00 F3 (0.66) F3SIRT5CYP3A4MAPK1OXTR
SCHEMBL5799222 0.91 ALOX5 (0.64) F3SIRT5CYP3A4MAPK1OXTR
SCHEMBL5799223 0.91 ALOX5 (0.64) F3SIRT5CYP3A4MAPK1OXTR
SCHEMBL2168639 0.90 F3 (0.80) F3SIRT5CYP3A4MAPK1OXTR
SCHEMBL1050015 0.89 F3 (0.82) F3SIRT5CYP3A4MAPK1OXTR
SCHEMBL5798114 0.89 PTPN1 (0.65) F3SIRT5CYP3A4MAPK1OXTR
SCHEMBL5798116 0.89 PTPN1 (0.65) F3SIRT5CYP3A4MAPK1OXTR
SCHEMBL5797983 0.85 PTPN1 (0.80) F3SIRT5PTPN1PTPN2GPBAR1
SCHEMBL5797986 0.85 PTPN1 (0.80) F3SIRT5PTPN1PTPN2GPBAR1
Maslinic Acid SCHEMBL20595803 0.81 PTPN1 (0.79) F3SIRT5CYP3A4MAPK1OXTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060235078-A1 Insulin secretion potentiator USE-TECHNO CORPORATION 2006-10-19 — — US disclosed
EP-1674089-A1 ACCELERATOR FOR INITIAL INSULIN SECRETION Use-Techno Corporation (JP) 2006-06-28 — — EP disclosed
WO-2006064583-A1 TERPENE, METHOD FOR DETERMINING ITS BLOOD CONCENTRATION, AND METHOD FOR ANALYZING ITS PHARMACOKINETICS USE-TECHNO CORPORATION (JP) 2006-06-22 — — WO disclosed
WO-2006054370-A1 GLUCONEOGENESIS INHIBITING AGENT USE-TECHNO CORPORATION (JP) 2006-05-26 — — WO disclosed
US-20050143464-A1 With low side effects, which rapidly stimulate early insulin secretion and suppress blood glucose increase only at mealtimes; antidiabetic agent; triterpene acids or alcohols with picene ring; corosolic acids; oleanene acids; ursenoic acids; banaba plant extracts USE-TECHNO CORPORATION 2005-06-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050143464-A1 With low side effects, which rapidly stimulate early insulin secretion and suppress blood glucose increase only at mealtimes; antidiabetic agent; triterpene acids or alcohols with picene ring; corosolic acids; oleanene acids; ursenoic acids; banaba plant extracts GPR119, IRS1, AMY1A F3 3246/4885SIRT5 4353/4885CYP3A4 1281/4885
US-20060235078-A1 Insulin secretion potentiator IAPP, GPR119, IRS1 F3 1070/4885SIRT5 4217/4885CYP3A4 1464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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