Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.64 |
| ▸ | F3 | P13726 | 2/20 | 0.59 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | OXTR | P30559 | 1/20 | 0.59 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.59 |
| ▸ | CD81 | P60033 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.52 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.52 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.52 |
| ▸ | PYGM | P11217 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799223 | 1.00 | ALOX5 (0.64) | ALOX5F3SIRT5CYP3A4MAPK1 | |
| SCHEMBL5797162 | 0.91 | F3 (0.66) | F3SIRT5CYP3A4MAPK1OXTR | |
| SCHEMBL5797167 | 0.91 | F3 (0.66) | F3SIRT5CYP3A4MAPK1OXTR | |
| SCHEMBL5795892 | 0.90 | F3 (0.74) | ALOX5F3SIRT5CYP3A4MAPK1 | |
| SCHEMBL5795891 | 0.90 | F3 (0.74) | ALOX5F3SIRT5CYP3A4MAPK1 | |
| SCHEMBL30013730 | 0.90 | F3 (0.74) | ALOX5F3SIRT5CYP3A4MAPK1 | |
| SCHEMBL5798114 | 0.88 | PTPN1 (0.65) | ALOX5F3SIRT5CYP3A4MAPK1 | |
| SCHEMBL5798116 | 0.88 | PTPN1 (0.65) | ALOX5F3SIRT5CYP3A4MAPK1 | |
| SCHEMBL2168639 | 0.85 | F3 (0.80) | ALOX5F3SIRT5CYP3A4MAPK1 | |
| SCHEMBL1050015 | 0.81 | F3 (0.82) | ALOX5F3SIRT5CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060235078-A1 | Insulin secretion potentiator | USE-TECHNO CORPORATION | 2006-10-19 | — | — | US | disclosed |
| EP-1674089-A1 | ACCELERATOR FOR INITIAL INSULIN SECRETION | Use-Techno Corporation (JP) | 2006-06-28 | — | — | EP | disclosed |
| WO-2006064583-A1 | TERPENE, METHOD FOR DETERMINING ITS BLOOD CONCENTRATION, AND METHOD FOR ANALYZING ITS PHARMACOKINETICS | USE-TECHNO CORPORATION (JP) | 2006-06-22 | — | — | WO | disclosed |
| WO-2006054370-A1 | GLUCONEOGENESIS INHIBITING AGENT | USE-TECHNO CORPORATION (JP) | 2006-05-26 | — | — | WO | disclosed |
| US-20050143464-A1 | With low side effects, which rapidly stimulate early insulin secretion and suppress blood glucose increase only at mealtimes; antidiabetic agent; triterpene acids or alcohols with picene ring; corosolic acids; oleanene acids; ursenoic acids; banaba plant extracts | USE-TECHNO CORPORATION | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143464-A1 | With low side effects, which rapidly stimulate early insulin secretion and suppress blood glucose increase only at mealtimes; antidiabetic agent; triterpene acids or alcohols with picene ring; corosolic acids; oleanene acids; ursenoic acids; banaba plant extracts | GPR119, IRS1, AMY1A | ALOX5 511/4885F3 3246/4885SIRT5 4353/4885 |
| US-20060235078-A1 | Insulin secretion potentiator | IAPP, GPR119, IRS1 | ALOX5 3951/4885F3 1070/4885SIRT5 4217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.