Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ACP1 | P24666 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799796 | 0.93 | MAPT (0.45) | MAPTKMT2AMEN1LMNAACP1 | |
| SCHEMBL5796715 | 0.92 | MAPT (0.46) | MAPTKMT2AMEN1LMNAACP1 | |
| SCHEMBL5822231 | 0.85 | KMT2A (0.48) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL5808427 | 0.84 | MAPT (0.48) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL5808433 | 0.84 | MAPT (0.48) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL5799063 | 0.79 | RAB9A (0.48) | MAPTKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL5799782 | 0.79 | MAPT (0.59) | MAPTKMT2AMEN1LMNAACP1 | |
| SCHEMBL5799236 | 0.78 | SCD (0.47) | MAPTKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL5796348 | 0.78 | MEN1 (0.41) | MAPTKMT2AMEN1LMNAACP1 | |
| SCHEMBL5799747 | 0.77 | MAPT (0.44) | MAPTKMT2AMEN1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |