Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808427 | 1.00 | MAPT (0.48) | MAPTLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL5799747 | 0.93 | MAPT (0.44) | MAPTLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL5799742 | 0.93 | MAPT (0.44) | MAPTLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL5799066 | 0.87 | KMT2A (0.47) | MAPTLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL5823606 | 0.86 | PIN1 (0.40) | MAPTKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL5797235 | 0.84 | MAPT (0.48) | MAPTLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL5808425 | 0.81 | MAPT (0.42) | MAPTLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL5799332 | 0.81 | RAB9A (0.47) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL5799330 | 0.81 | RAB9A (0.47) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL5799794 | 0.80 | MCL1 (0.41) | MAPTLMNAKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |