Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16108114 | 0.82 | KMT2A (0.49) | KMT2ARIPK1ALDH1A1LMNANPC1 | |
| SCHEMBL20027156 | 0.82 | ALOX12 (0.69) | KMT2AALDH1A1LMNAMAPTHPGD | |
| SCHEMBL2456852 | 0.80 | KMT2A (0.58) | KMT2ARIPK1ALDH1A1LMNANPC1 | |
| SCHEMBL20496870 | 0.79 | RIPK1 (0.50) | KMT2ARIPK1ALDH1A1NPC1RAB9A | |
| SCHEMBL28101463 | 0.79 | GAA (0.58) | KMT2ARIPK1ALDH1A1LMNANPC1 | |
| SCHEMBL7797848 | 0.77 | LMNA (0.47) | KMT2ARIPK1ALDH1A1LMNANPC1 | |
| SCHEMBL2905172 | 0.76 | KMT2A (0.77) | KMT2ARIPK1ALDH1A1LMNAMAPT | |
| SCHEMBL31426228 | 0.76 | RIPK1 (0.58) | KMT2ARIPK1ALDH1A1LMNANPC1 | |
| SCHEMBL4018473 | 0.74 | KMT2A (0.49) | KMT2ARIPK1ALDH1A1LMNANPC1 | |
| SCHEMBL5797350 | 0.74 | KMT2A (0.57) | KMT2ARIPK1ALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006037468-A1 | HIV REVERSE TRANSCRIPTASE INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2006-04-13 | — | — | WO | claimed |