Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799057 | 0.91 | HDAC6 (0.52) | MAPTKDM4ESMN1; SMN2HDAC6HDAC3 | |
| SCHEMBL5796597 | 0.90 | MAPT (0.43) | MAPTMCL1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL5799741 | 0.83 | ALDH1A1 (0.40) | MAPTMCL1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL5799654 | 0.82 | NPC1 (0.39) | MAPTMCL1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL5819578 | 0.81 | HDAC6 (0.41) | KDM4EHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL5796765 | 0.80 | MAPT (0.41) | MAPTMCL1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL5799640 | 0.79 | MAPT (0.52) | MAPTMCL1KDM4EKMT2APOLB | |
| SCHEMBL5799662 | 0.77 | HDAC6 (0.48) | MAPTMCL1KDM4EHDAC6HDAC3 | |
| SCHEMBL5799682 | 0.77 | NPC1 (0.39) | MAPTMCL1HDAC6HDAC3HDAC1 | |
| SCHEMBL5799923 | 0.77 | GCGR (0.43) | MAPTMCL1KDM4EKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |