Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797642 | 0.90 | HDAC6 (0.44) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5796765 | 0.89 | MAPT (0.41) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5799659 | 0.88 | MTNR1A (0.41) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5799923 | 0.88 | GCGR (0.43) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5799741 | 0.84 | ALDH1A1 (0.40) | MAPTKMT2AKDM4EALDH1A1MCL1 | |
| SCHEMBL5799682 | 0.82 | NPC1 (0.39) | MAPTMEN1KMT2AALDH1A1MCL1 | |
| SCHEMBL5797676 | 0.82 | HDAC6 (0.42) | MAPTMCL1HTT | |
| SCHEMBL5823657 | 0.81 | ALDH1A1 (0.46) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL5799447 | 0.81 | HDAC6 (0.43) | ALDH1A1ACP3 | |
| SCHEMBL5796946 | 0.81 | MTNR1A (0.43) | MAPTMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |