Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819578 | 0.91 | HDAC6 (0.41) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL5797634 | 0.90 | MAPT (0.44) | MAPTMCL1ALDH1A1KDM4EHPGD | |
| SCHEMBL5799741 | 0.82 | ALDH1A1 (0.40) | MAPTMCL1ALDH1A1KDM4ENPC1 | |
| SCHEMBL5799057 | 0.81 | HDAC6 (0.52) | MAPTKDM4ESMN1; SMN2KMT2APOLB | |
| SCHEMBL5799654 | 0.81 | NPC1 (0.39) | MAPTMCL1ALDH1A1KDM4EHPGD | |
| SCHEMBL5796765 | 0.79 | MAPT (0.41) | MAPTMCL1ALDH1A1KDM4EHPGD | |
| SCHEMBL5799640 | 0.79 | MAPT (0.52) | MAPTMCL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL5799682 | 0.77 | NPC1 (0.39) | MAPTMCL1ALDH1A1NPC1RAB9A | |
| SCHEMBL5799923 | 0.76 | GCGR (0.43) | MAPTMCL1ALDH1A1KDM4EHPGD | |
| SCHEMBL5799659 | 0.75 | MTNR1A (0.41) | MAPTMCL1ALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |