Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5795637 | 0.93 | HDAC1 (0.37) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5796436 | 0.92 | HDAC1 (0.45) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5799923 | 0.87 | GCGR (0.43) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5799659 | 0.85 | MTNR1A (0.41) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5812472 | 0.84 | NPC1 (0.40) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5799741 | 0.83 | ALDH1A1 (0.40) | NPC1RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL5796765 | 0.83 | MAPT (0.41) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5799640 | 0.82 | MAPT (0.52) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL5823657 | 0.81 | ALDH1A1 (0.46) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5796946 | 0.78 | MTNR1A (0.43) | NPC1RAB9AKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |