Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820977 | 0.91 | ALDH1A1 (0.53) | MAPTALDH1A1HTTHSD17B10RAB9A | |
| SCHEMBL5820244 | 0.86 | MAPT (0.49) | MAPTALDH1A1HTTHSD17B10RAB9A | |
| SCHEMBL5799050 | 0.85 | MAPT (0.55) | MAPTALDH1A1HTTHSD17B10RAB9A | |
| SCHEMBL5799655 | 0.84 | RAB9A (0.51) | MAPTALDH1A1HTTRAB9AKMT2A | |
| SCHEMBL5799858 | 0.83 | MAPT (0.56) | MAPTALDH1A1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL5799862 | 0.83 | MAPT (0.56) | MAPTALDH1A1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL5797705 | 0.82 | MAPT (0.49) | MAPTALDH1A1HTTRAB9AKMT2A | |
| SCHEMBL5810687 | 0.82 | MAPT (0.49) | MAPTALDH1A1HTTRAB9AKMT2A | |
| SCHEMBL5797060 | 0.81 | RAB9A (0.57) | MAPTRAB9AKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL5799593 | 0.81 | NPC1 (0.47) | MAPTALDH1A1HTTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |