Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797667 | 0.91 | MAPT (0.54) | ALDH1A1MAPTRAB9AHTTHSD17B10 | |
| SCHEMBL5820244 | 0.77 | MAPT (0.49) | ALDH1A1MAPTRAB9AHTTHSD17B10 | |
| SCHEMBL28612693 | 0.75 | MEN1 (0.73) | ALDH1A1RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL5799050 | 0.75 | MAPT (0.55) | ALDH1A1MAPTRAB9AHTTHSD17B10 | |
| SCHEMBL5799655 | 0.74 | RAB9A (0.51) | ALDH1A1MAPTRAB9AHTTKMT2A | |
| SCHEMBL6304948 | 0.74 | MEN1 (0.59) | ALDH1A1MAPTRAB9AHTTKMT2A | |
| SCHEMBL839926 | 0.74 | MEN1 (0.69) | ALDH1A1MAPTRAB9AHTTHSD17B10 | |
| Acedoben SCHEMBL24320 | 0.73 | ALDH1A1 (0.68) | ALDH1A1MAPTRAB9AHTTHSD17B10 | |
| SCHEMBL25195104 | 0.73 | MAPT (0.66) | ALDH1A1MAPTRAB9AHTTHSD17B10 | |
| SCHEMBL5799862 | 0.73 | MAPT (0.56) | ALDH1A1MAPTRAB9AKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |