Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5795301 | 0.85 | NPC1 (0.56) | MAPTGFERNPC1RAB9AKMT2A | |
| SCHEMBL5797991 | 0.81 | NPC1 (0.59) | MAPTGFERNPC1RAB9APPARG | |
| SCHEMBL5797579 | 0.81 | KMT2A (0.55) | MAPTGFERNPC1RAB9APPARG | |
| SCHEMBL488306 | 0.80 | S1PR4 (0.71) | MAPTNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL16295397 | 0.79 | MAPT (0.64) | MAPTGFERNPC1RAB9APPARG | |
| SCHEMBL5797568 | 0.79 | ALDH1A1 (0.52) | MAPTGFERNPC1RAB9AKMT2A | |
| SCHEMBL5797255 | 0.78 | NPC1 (0.65) | MAPTGFERNPC1RAB9AKMT2A | |
| SCHEMBL2770576 | 0.76 | INPPL1 (0.54) | INPPL1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL3576759 | 0.76 | INPPL1 (0.54) | INPPL1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL5797499 | 0.75 | MGMT (0.55) | MAPTNPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |