Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797881 | 1.00 | PTGS2 (0.36) | PTGS2TSHRLMNAKMT2ASLC6A2 | |
| SCHEMBL5801013 | 0.95 | ESR1 (0.38) | PTGS2TSHRESR1 | |
| SCHEMBL5801009 | 0.95 | ESR1 (0.38) | PTGS2TSHRESR1 | |
| SCHEMBL5808086 | 0.94 | PTGS2 (0.36) | PTGS2TSHRSMYD3 | |
| SCHEMBL5808087 | 0.94 | PTGS2 (0.36) | PTGS2TSHRSMYD3 | |
| SCHEMBL5799882 | 0.94 | TSHR (0.39) | PTGS2TSHRLMNAKMT2AHPGD | |
| SCHEMBL5799881 | 0.94 | TSHR (0.39) | PTGS2TSHRLMNAKMT2AHPGD | |
| SCHEMBL5798592 | 0.91 | PTGS2 (0.44) | PTGS2 | |
| SCHEMBL5800660 | 0.91 | PTGS2 (0.37) | PTGS2KMT2A | |
| SCHEMBL5798596 | 0.91 | PTGS2 (0.44) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |