Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 3/20 | 0.41 |
| ▸ | SI | P14410 | 3/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.40 |
| ▸ | CDK4 | P11802 | 3/20 | 0.40 |
| ▸ | CCND1 | P24385 | 3/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31268114 | 0.79 | MEN1 (0.67) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL8591131 | 0.79 | MEN1 (0.67) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL5801042 | 0.73 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5801006 | 0.70 | KMT2A (0.43) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL27960948 | 0.70 | MEN1 (0.59) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL5801051 | 0.70 | MEN1 (0.51) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL31268138 | 0.69 | MEN1 (0.55) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL820361 | 0.67 | IDO1 (0.61) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL5997097 | 0.66 | MEN1 (0.51) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL28229390 | 0.66 | GPR84 (0.53) | MEN1KMT2AGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006070292-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (US) | 2006-07-06 | — | — | WO | disclosed |