Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800812 | 1.00 | TSHR (0.44) | TSHRL3MBTL1KDM4ELMNACYP1A2 | |
| SCHEMBL5798332 | 0.72 | NPC1 (0.40) | L3MBTL1KDM4ECYP2D6SCN1ASCN2A | |
| SCHEMBL5798028 | 0.72 | KMT2A (0.43) | TSHRL3MBTL1CYP2D6SCN1ASCN2A | |
| SCHEMBL5801196 | 0.72 | NPC1 (0.40) | L3MBTL1KDM4ECYP2D6SCN1ASCN2A | |
| SCHEMBL5799304 | 0.72 | KMT2A (0.43) | TSHRL3MBTL1CYP2D6SCN1ASCN2A | |
| SCHEMBL27419336 | 0.70 | MMP8 (0.41) | TSHRKDM4ELMNAKMT2AMEN1 | |
| SCHEMBL27419339 | 0.70 | MMP8 (0.41) | TSHRKDM4ELMNAKMT2AMEN1 | |
| SCHEMBL5801142 | 0.68 | CYP26A1 (0.40) | L3MBTL1CYP1A2KMT2AMEN1ALDH1A1 | |
| SCHEMBL15943158 | 0.68 | MAPT (0.42) | LMNACYP1A2KMT2AMEN1GAA | |
| SCHEMBL16840480 | 0.66 | AAK1 (0.41) | L3MBTL1KDM4ECYP2D6SCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030208-A1 | AMINO ACID | UNIVERSITY OF LEEDS (GB) | 2006-03-23 | — | — | WO | disclosed |