Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | F2R | P25116 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29466485 | 0.93 | NPC1 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL166193 | 0.93 | NPC1 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL1483201 | 0.80 | MAPT (0.52) | SMN1; SMN2MAPTHTT | |
| SCHEMBL19968665 | 0.80 | MAPT (0.52) | SMN1; SMN2MAPT | |
| SCHEMBL17297757 | 0.78 | ALDH1A1 (0.43) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL1188598 | 0.77 | G6PD (0.39) | SMN1; SMN2MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL5109153 | 0.77 | KMT2A (0.45) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL28427057 | 0.76 | ALDH1A1 (0.64) | SMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL1873518 | 0.76 | KMT2A (0.41) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL279655 | 0.75 | ALDH1A1 (0.53) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006057503-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPARϜ AND PPARα, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2006-06-01 | — | — | WO | disclosed |