Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.50 |
| ▸ | HNF4A | P41235 | 2/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.45 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103552 | 0.89 | HPGD (0.51) | MAPTSMN1; SMN2AKR1C3AKR1C2HSD11B1 | |
| SCHEMBL19968665 | 0.85 | MAPT (0.52) | MAPTSMN1; SMN2ACMSDHNF4AAKR1C4 | |
| Acetophenone SCHEMBL1481981 | 0.85 | MAPT (0.58) | MAPTSMN1; SMN2ACMSDHNF4AAKR1C4 | |
| SCHEMBL27918808 | 0.85 | ACMSD (0.63) | ACMSDHNF4AAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL6626508 | 0.84 | HSD17B1 (0.44) | MAPTSMN1; SMN2MCL1HSD17B1KDM4E | |
| SCHEMBL7376306 | 0.84 | HSD17B1 (0.44) | MAPTSMN1; SMN2ACMSDHNF4AAKR1C4 | |
| SCHEMBL5798650 | 0.80 | SMN1; SMN2 (0.48) | MAPTSMN1; SMN2HTT | |
| SCHEMBL11435938 | 0.79 | MAPT (0.53) | MAPTSMN1; SMN2ACMSDHNF4AHSD11B1 | |
| SCHEMBL4216869 | 0.79 | ACMSD (0.72) | MAPTSMN1; SMN2ACMSDHNF4AHSD11B1 | |
| SCHEMBL7673881 | 0.79 | ACMSD (0.61) | MAPTSMN1; SMN2ACMSDHNF4AAKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368346-B | 1, 4-benzodioxane-benzimidazole salt compound and synthesis method and application thereof | 曲靖师范学院 | 2024-04-09 | — | — | CN | claimed |
| CN-115368346-A | 1, 4-benzodioxan-benzimidazole salt compound and synthesis method and application thereof | 曲靖师范学院 | 2022-11-22 | — | — | CN | claimed |
| EP-1140877-A1 | HYPOLIPIDEMIC AND ANTIOXIDANT MORPHOLINE DERIVATIVES | Elpen S.A. . (GR) | 2001-10-10 | — | — | EP | claimed |
| WO-2000042030-A1 | HYPOLIPIDEMIC AND ANTIOXIDANT MORPHOLINE DERIVATIVES | ELPEN S.A. (GR) | 2000-07-20 | — | — | WO | claimed |
| CN-115368346-B | 1, 4-benzodioxane-benzimidazole salt compound and synthesis method and application thereof | 曲靖师范学院 | 2024-04-09 | — | — | CN | disclosed |
| CN-117820192-A | Gamma-lactam ring compound and preparation method and application thereof | 重庆理工大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-117683026-A | 3-tetrahydrofuran chromone compound and diastereoisomeric divergent preparation method and application thereof | 广州中医药大学(广州中医药研究院) | 2024-03-12 | — | — | CN | disclosed |
| CN-114702501-B | Imidazole peptide deformylase inhibitor with anti-tumor effect | 中山大学 | 2023-10-17 | — | — | CN | disclosed |
| CN-108727171-B | Preparation method of 4,4' -di (2-bromoacetyl) biphenyl | 上海迪赛诺化学制药有限公司 | 2023-06-16 | — | — | CN | disclosed |
| EP-3487865-B1 | DINUCLEAR AND OLIGONUCLEAR METAL COMPLEXES CONTAINING TRIPODAL BIDENTATE PART LIGANDS AND THEIR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2022-11-23 | — | — | EP | disclosed |
| CN-115368346-A | 1, 4-benzodioxan-benzimidazole salt compound and synthesis method and application thereof | 曲靖师范学院 | 2022-11-22 | — | — | CN | disclosed |
| CN-110642778-B | Viologen compound, preparation method and application thereof | 淮阴师范学院 | 2022-10-04 | — | — | CN | disclosed |
| WO-1998008839-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED THIOPHENE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |
| WO-1998008813-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED PYRROLIDINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |
| WO-1997026300-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES | ELI LILLY AND COMPANY (US) | 1997-07-24 | — | — | WO | disclosed |
| EP-0726900-A1 | 7H-IMIDAZO(1,2-a)PYRAZINE-8-ONE NMDA RECEPTOR ANTAGONISTS | Aventis Pharma S.A. (FR) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012594-A1 | 7H-IMIDAZO(1,2-a)PYRAZINE-8-ONE NMDA RECEPTOR ANTAGONISTS | RHONE-POULENC RORER S.A. (FR) | 1995-05-11 | — | — | WO | disclosed |
| US-4376162-A | ORGANIC SILVER SALT, PHOTOCATALYST, REDUCING AGENT | FUJI PHOTO FILM CO., LTD. (JP) | 1983-03-08 | — | — | US | disclosed |
| US-4359524-A | ANTIHALATION LAYER OF HALOGEN COMPOUND AND MEROCYANIN DYE | FUJI PHOTO FILM CO., LTD. (JP) | 1982-11-16 | — | — | US | disclosed |
| US-4244952-A | Imidazo[2',1':2,3]-thiazolo[5,4-c]pyridines and composition thereof for treating immune diseases | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1981-01-13 | — | — | US | disclosed |