SCHEMBL166193

SCHEMBL166193

CC(=O)c1ccccc1Br

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.52
RAB9A P51151 5/20 0.52
SMN1; SMN2 Q16637 4/20 0.49
ALDH1A1 P00352 4/20 0.49
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
HPGD P15428 1/20 0.47
F2R P25116 2/20 0.45
HTT P42858 1/20 0.45
CASP3 P42574 1/20 0.45
SENP8 Q96LD8 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29466485 1.00 NPC1 (0.52) NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A
SCHEMBL5798650 0.93 SMN1; SMN2 (0.48) NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A
SCHEMBL17297757 0.84 ALDH1A1 (0.43) NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A
SCHEMBL5109153 0.82 KMT2A (0.45) NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A
SCHEMBL1188598 0.82 G6PD (0.39) NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A
SCHEMBL1873518 0.81 KMT2A (0.41) NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A
SCHEMBL279655 0.81 ALDH1A1 (0.53) SMN1; SMN2ALDH1A1KMT2AMEN1HPGD
SCHEMBL6469935 0.79 ALDH1A1 (0.40) NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A
SCHEMBL30779705 0.79 THRB (0.41) NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A
SCHEMBL1854505 0.79 THRB (0.41) NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115109759-B Carbonyl reductase LsCR mutant, engineering bacterium and application thereof in preparation of chiral alcohol by asymmetric reduction of carbonyl compound 浙江工业大学 2024-05-03 CN claimed
CN-111065744-B Method for producing chiral amines 威妥有限公司 2024-05-03 CN claimed
US-11925630-B1 6′-(2-bromophenyl)-2′-methoxy-3,4′-bipyridine-3′-carbonitrile as an antioxidant compound King Faisal University (SA) 2024-03-12 US claimed
WO-2024046712-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2024-03-07 WO claimed
US-11919861-B1 6′-(2-bromophenyl)-2′-ethoxy-3,4′-bipyridine-3′-carbonitrile as an antioxidant compound King Faisal University (SA) 2024-03-05 US claimed
EP-4175045-B1 COATED SEPARATOR WITH HIGH HEAT RESISTANCE AND HIGH PEEL STRENGTH AND PREPARATION METHOD THEREOF JIANGSU HORIZON NEW ENERGY TECH CO LTD (CN) 2023-10-11 EP claimed
CN-113991250-B High-heat-resistance high-peel strength coated diaphragm and preparation method thereof 江苏厚生新能源科技有限公司 2023-09-01 CN claimed
CN-116178365-A Berberine hydrochloride derivative and preparation method and application thereof 常州大学 2023-05-30 CN claimed
EP-4175045-A1 COATED SEPARATOR WITH HIGH HEAT RESISTANCE AND HIGH PEEL STRENGTH AND PREPARATION METHOD THEREOF Jiangsu Horizon New Energy Tech Co., Ltd (CN) 2023-05-03 EP claimed
CN-115925527-A Method for preparing alpha-diaryl methyl substituted ketone compound 湖南理工学院 2023-04-07 CN claimed
WO-2009050366-A2 ARYLAMINE SYNTHESIS METHOD CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2009-04-23 WO claimed
EP-1868604-A2 REGULATION OF PROTEIN SYNTHESIS BY INHIBITION OF EIF4E-EIF4G INTERACTION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2007-12-26 EP claimed
WO-2006078942-A2 REGULATION OF PROTEIN SYNTHESIS BY INHIBITION OF EIF4E-EIF4G INTERACTION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2006-07-27 WO claimed
EP-0912467-B1 ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE RHODIA CHIMIE SA (FR) 2002-04-24 EP claimed
EP-0674233-B1 Recording sheets XEROX CORP (US) 2000-05-24 EP claimed
US-5928765-A Recording sheets XEROX CORPORATION (US) 1999-07-27 US claimed
EP-0912467-A1 ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE RHODIA CHIMIE (FR) 1999-05-06 EP claimed
WO-1998000375-A1 ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE RHODIA CHIMIE (FR) 1998-01-08 WO claimed
EP-0674233-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed
US-4048036-A CURING, PHOTOINITIATOR PPG INDUSTRIES, INC. (US) 1977-09-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11925630-B1 6′-(2-bromophenyl)-2′-methoxy-3,4′-bipyridine-3′-carbonitrile as an antioxidant compound GPX4, GPX1, CAT NPC1 1715/4885RAB9A 3176/4885SMN1; SMN2 1130/4885
US-11919861-B1 6′-(2-bromophenyl)-2′-ethoxy-3,4′-bipyridine-3′-carbonitrile as an antioxidant compound GPX4, GPX1, CAT NPC1 1638/4885RAB9A 3173/4885SMN1; SMN2 1389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.