Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4909578 | 1.00 | HCAR2 (0.54) | HCAR2LMNAMAPK1CES2CES1 | |
| SCHEMBL9764591 | 0.95 | LMNA (0.52) | HCAR2LMNAMAPK1CES2CES1 | |
| SCHEMBL28905351 | 0.83 | LMNA (0.51) | HCAR2LMNAMAPK1CYP2D6CYP2C9 | |
| SCHEMBL352390 | 0.81 | LMNA (0.62) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL1951103 | 0.81 | LMNA (0.62) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL4909583 | 0.77 | LMNA (0.78) | HCAR2LMNAMAPK1CES2CES1 | |
| Mandelic Acid SCHEMBL4909573 | 0.77 | LMNA (0.78) | HCAR2LMNAMAPK1CES2CES1 | |
| Mandelic Acid SCHEMBL5798900 | 0.77 | LMNA (0.78) | HCAR2LMNAMAPK1CES2CES1 | |
| SCHEMBL2687707 | 0.77 | LMNA (0.58) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL378836 | 0.74 | LMNA (0.54) | LMNAMAPK1CES2CES1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108079004-A | The application of amphotericin B and its derivative in quick anti-depression drug is prepared | 南通大学 | 2018-05-29 | — | — | CN | disclosed |
| CN-106265685-A | Myrrha sterone Z application in preparing anti-depression drug | 南通大学 | 2017-01-04 | — | — | CN | disclosed |
| WO-2006059347-A2 | IMPROVED PROCESS FOR PREPARATION OF RAMIPRIL | MOREPEN LABORATORIES LIMITED (IN) | 2006-06-08 | — | — | WO | disclosed |