Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798907 | 0.95 | HCAR2 (0.54) | LMNAMAPK1CES2CES1HCAR2 | |
| SCHEMBL4909578 | 0.95 | HCAR2 (0.54) | LMNAMAPK1CES2CES1HCAR2 | |
| SCHEMBL28905351 | 0.88 | LMNA (0.51) | LMNAMAPK1HCAR2CYP2D6CYP2C9 | |
| SCHEMBL1951103 | 0.86 | LMNA (0.62) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL352390 | 0.86 | LMNA (0.62) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL2687707 | 0.82 | LMNA (0.58) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL11083519 | 0.78 | LMNA (0.54) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL378836 | 0.78 | LMNA (0.54) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL1040186 | 0.78 | LMNA (0.54) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL2761810 | 0.78 | LMNA (0.54) | LMNAMAPK1CES2CES1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021413-A | Analgesic thiomorpholins their preparation, and pharmaceutical compositions containing them | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |