SCHEMBL579900

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL579469	0.89	OPRM1 (0.67)	RAB9AOPRM1OPRD1OPRK1ADRB2
	SCHEMBL579511	0.88	OPRM1 (0.61)	RAB9AOPRM1OPRD1OPRK1NAMPT
	2-Picolinic Acid SCHEMBL5740572	0.88	RAB9A (0.52)	RAB9AOPRM1OPRD1OPRK1NAMPT
	2-Picolinic Acid SCHEMBL5740570	0.87	OPRM1 (0.59)	RAB9AOPRM1OPRD1OPRK1NAMPT
	SCHEMBL5751520	0.84	OPRM1 (0.58)	RAB9AOPRM1OPRD1OPRK1NAMPT
	SCHEMBL11617534	0.83	RAB9A (0.75)	RAB9ANAMPTKMT2ANPC1SMN1; SMN2
	SCHEMBL5751517	0.83	OPRM1 (0.72)	OPRM1OPRD1OPRK1NAMPTADRB2
	SCHEMBL579444	0.82	OPRM1 (0.60)	RAB9AOPRM1OPRD1OPRK1KMT2A
	SCHEMBL580095	0.82	NAMPT (0.60)	OPRM1OPRD1OPRK1NAMPTADRB1
	SCHEMBL12310174	0.82	KMT2A (0.76)	RAB9AKMT2ANPC1SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.