Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.50 |
| ▸ | CES2 | O00748 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA4 | P22748 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA3 | P07451 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27512238 | 0.86 | CES2 (0.50) | CES1CES2ALDH1A1TSHRALOX15 | |
| Benzoic Acid SCHEMBL1785802 | 0.81 | TSHR (0.82) | CES1CES2ALDH1A1TSHRDAO | |
| Terephthalic Acid SCHEMBL7526066 | 0.81 | TSHR (0.72) | CES1CES2ALDH1A1TSHRALOX15 | |
| SCHEMBL9312487 | 0.78 | KMT2A (0.47) | ALDH1A1MAPTCYP2C19SMN1; SMN2MAPK1 | |
| Propionic Acid SCHEMBL9312830 | 0.78 | FFAR3 (0.56) | CES1CES2ALDH1A1TSHRALOX15 | |
| SCHEMBL49871 | 0.78 | ALOX12 (0.46) | ALDH1A1TSHRALOX15TDP1CA2 | |
| SCHEMBL58153 | 0.78 | ALOX12 (0.46) | ALDH1A1TSHRALOX15TDP1CA2 | |
| Biphenyl SCHEMBL190337 | 0.77 | ALDH1A1 (0.69) | CES1CES2ALDH1A1TSHRALOX15 | |
| Naphthalene SCHEMBL3278833 | 0.77 | CYP2A6 (0.61) | CES1CES2ALDH1A1TSHRALOX15 | |
| Bicarbonate SCHEMBL7644062 | 0.77 | CES1 (0.50) | CES1CES2ALDH1A1TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111073167-A | Thermoplastic resin composition and resin molded article | 旭化成株式会社 | 2020-04-28 | — | — | CN | disclosed |
| CN-111019259-A | Thermoplastic resin composition and molded article | 旭化成株式会社 | 2020-04-17 | — | — | CN | disclosed |
| CN-102483598-B | Electrophotographic belt and electrophotographic apparatus | CANON KK | 2015-04-01 | — | — | CN | disclosed |
| CN-103748174-A | Uncoated housing and method for manufacturing same | ASAHI KASEI CHEMICALS CORP | 2014-04-23 | — | — | CN | disclosed |
| CN-102483598-A | Electrophotographic belt and electrophotographic apparatus | CANON KK | 2012-05-30 | — | — | CN | disclosed |
| CN-102037567-A | Back surface protective film for solar cell and solar cell module having same | TECHNO POLYMER CO LTD | 2011-04-27 | — | — | CN | disclosed |
| WO-2006027110-A1 | METHOD FOR THE PRODUCTION OF POLYCARBONATE | BAYER MATERIALSCIENCE AG (DE) | 2006-03-16 | — | — | WO | disclosed |
| CN-1097616-C | Thermoplastic resin composition and method of producing the same | POLYPLASTICS CO (JP) | 2003-01-01 | — | — | CN | disclosed |
| JP-2002053658-A | METHOD FOR PRODUCING AROMATIC POLYCARBONATE | ASAHI KASEI CORP | 2002-02-19 | — | — | JP | disclosed |
| JP-2002047344-A | METHOD FOR MANUFACTURING AROMATIC POLYCARBONATE | ASAHI KASEI CORP | 2002-02-12 | — | — | JP | disclosed |
| JP-2002030142-A | PROCESS FOR PRODUCING AROMATIC POLYCARBONATE | ASAHI KASEI CORP | 2002-01-31 | — | — | JP | disclosed |
| CN-1170735-A | Thermoplastic resin composition and method of producing the same | POLYPLASTICS CO (JP) | 1998-01-21 | — | — | CN | disclosed |
| US-5079127-A | Methine Dyes | CANON KABUSHIKI KAISHA (JP) | 1992-01-07 | — | — | US | disclosed |
| US-5079128-A | Thin film containing a methine dye having at least two dimethylaminophenyl groups and a carbonium ion; laser writing; heat resistance | CANON KABUSHIKI KAISHA (JP) | 1992-01-07 | — | — | US | disclosed |
| CN-88102619-A | The thermoplastic resin composition | — | 1988-11-30 | — | — | CN | disclosed |