Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042630 | 0.93 | L3MBTL1 (0.61) | L3MBTL1PAOXSMN1; SMN2KEAP1SIGMAR1 | |
| SCHEMBL2852219 | 0.89 | L3MBTL1 (0.65) | L3MBTL1PAOXSMN1; SMN2TSHRLMNA | |
| Hydrochloric Acid SCHEMBL7430675 | 0.87 | L3MBTL1 (0.63) | L3MBTL1PAOXSMN1; SMN2TSHRLMNA | |
| SCHEMBL2091283 | 0.87 | PAOX (0.60) | L3MBTL1PAOXSMN1; SMN2TSHRHTR7 | |
| Hydrochloric Acid SCHEMBL7427001 | 0.85 | PAOX (0.58) | L3MBTL1PAOXSMN1; SMN2TSHRHTR7 | |
| SCHEMBL30479937 | 0.83 | PAOX (0.72) | L3MBTL1PAOXTSHRHTR7SIGMAR1 | |
| SCHEMBL248151 | 0.82 | KEAP1 (0.56) | PAOXSMN1; SMN2KEAP1SIGMAR1CYP2D6 | |
| SCHEMBL31008699 | 0.81 | L3MBTL1 (0.68) | L3MBTL1PAOXSMN1; SMN2SIGMAR1MAPT | |
| SCHEMBL829653 | 0.81 | L3MBTL1 (0.50) | L3MBTL1PAOXSMN1; SMN2KEAP1SIGMAR1 | |
| Urea SCHEMBL11526333 | 0.80 | KEAP1 (0.54) | L3MBTL1PAOXSMN1; SMN2KEAP1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432702-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR USE AS RAF INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 2006-08-16 | — | — | EP | disclosed |