Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435341 | 0.83 | MMP8 (0.62) | — | |
| SCHEMBL9679740 | 0.81 | KMT2A (0.58) | KMT2ALMNAMEN1 | |
| SCHEMBL9678841 | 0.79 | KMT2A (0.55) | KMT2ALMNAMEN1 | |
| SCHEMBL9678830 | 0.79 | KMT2A (0.55) | KMT2ALMNAMEN1 | |
| SCHEMBL14849662 | 0.79 | NLRP3 (0.50) | KMT2ALMNA | |
| SCHEMBL9679386 | 0.79 | KMT2A (0.55) | KMT2ALMNAMEN1 | |
| SCHEMBL9679376 | 0.79 | KMT2A (0.55) | KMT2ALMNAMEN1 | |
| SCHEMBL6049324 | 0.78 | KMT2A (0.61) | KMT2ALMNAMEN1 | |
| SCHEMBL16589148 | 0.77 | — | — | |
| SCHEMBL5972840 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858336-A1 | METHOD AND PHARMACEUTICAL COMPOSITION FOR REGULATING LIPID CONCENTRATION | WARNER-LAMBERT COMPANY (US) | 1998-08-19 | — | — | EP | claimed |
| WO-1997016184-A1 | METHOD AND PHARMACEUTICAL COMPOSITION FOR REGULATING LIPID CONCENTRATION | WARNER-LAMBERT COMPANY (US) | 1997-05-09 | — | — | WO | claimed |
| EP-1203767-B1 | Heterocyclic-substituted alkylamide acat inhibitors | WARNER LAMBERT CO (US) | 2006-01-04 | — | — | EP | disclosed |
| EP-1203767-A1 | Heterocyclic-substituted alkylamide acat inhibitors | WARNER-LAMBERT COMPANY (US) | 2002-05-08 | — | — | EP | disclosed |
| US-5646170-A | ACYLCOENZYME A:CHOLESTEROL ACYLTRANSFERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1997-07-08 | — | — | US | disclosed |
| US-5441975-A | Anticholesterol agent | WARNER-LAMBERT COMPANY (US) | 1995-08-15 | — | — | US | disclosed |
| US-5366987-A | Enzyme inhibitors, anticholesterol | WARNER-LAMBERT COMPANY (US) | 1994-11-22 | — | — | US | disclosed |