Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10366257 | 0.79 | TSHR (0.30) | TSHR | |
| SCHEMBL5811359 | 0.75 | — | — | |
| SCHEMBL10743466 | 0.74 | GSK3B (0.32) | TSHRTRPA1 | |
| SCHEMBL4884095 | 0.74 | GSK3B (0.32) | TSHRTRPA1 | |
| SCHEMBL4811123 | 0.74 | GSK3B (0.32) | TSHRTRPA1 | |
| SCHEMBL25312495 | 0.72 | FFAR3 (0.40) | OR51E2 | |
| SCHEMBL5431327 | 0.72 | LDHA (0.42) | TSHROR51E2 | |
| SCHEMBL10507701 | 0.72 | TSHR (0.40) | TSHROR51E2 | |
| SCHEMBL9651208 | 0.72 | TSHR (0.40) | TSHROR51E2 | |
| SCHEMBL9651203 | 0.72 | TSHR (0.40) | TSHROR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031575-B | Preparation method of ethyl northioxomate | 山东金城医药化工有限公司 | 2023-09-12 | — | — | CN | disclosed |
| WO-2006067803-A1 | A NOVEL INTERMEDIATE FOR THE PREPARATION OF CEFEPIME | LUPIN LIMITED (IN) | 2006-06-29 | — | — | WO | disclosed |
| US-6846952-B2 | Process for manufacture of a 4-bromo-2-oxyimino butyric acid and its derivatives | LUPIN LIMITED (IN) | 2005-01-25 | — | — | US | disclosed |
| US-20040054224-A1 | Process for manufacture of a 4-bromo-2-oxyimino butyric acid and its derivatives | LUPIN LIMITED (IN) | 2004-03-18 | — | — | US | disclosed |
| WO-2003045899-A1 | AN IMPROVED PROCESS FOR MANUFACTURE OF 4-BROMO-2-OXYIMINO BUTYRIC ACID AND ITS DERIVATIVES | LUPIN LIMITED (IN) | 2003-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040054224-A1 | Process for manufacture of a 4-bromo-2-oxyimino butyric acid and its derivatives | GABRB1, BBOX1, GABRB2 | TSHR 682/4885TRPA1 3466/4885OR51E2 1626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.