Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | GRK2 | P25098 | 3/20 | 0.53 |
| ▸ | GRK3 | P35626 | 3/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.52 |
| ▸ | GRK5 | P34947 | 2/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | CTSV | O60911 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5810457 | 0.92 | GRK2 (0.52) | FFAR1GRK2GRK3GRK5SMN1; SMN2 | |
| SCHEMBL5796853 | 0.91 | HDAC6 (0.57) | FFAR1GRK2GRK3GRK5MAOB | |
| SCHEMBL5799597 | 0.85 | NPC1 (0.50) | GRK2GRK3GRK5SMN1; SMN2KMT2A | |
| SCHEMBL5799558 | 0.78 | ALDH1A1 (0.63) | NR1H4SMN1; SMN2KMT2AMEN1TDP1 | |
| SCHEMBL5795757 | 0.78 | POLB (0.49) | SRD5A2SMN1; SMN2KMT2AMEN1PKM | |
| SCHEMBL5798866 | 0.78 | PPIA (0.58) | RXRARXRBRXRG | |
| SCHEMBL5287947 | 0.78 | FFAR1 (0.62) | FFAR1GRK2GRK3NR4A2GRK5 | |
| SCHEMBL8009616 | 0.77 | FFAR1 (0.58) | FFAR1GRK2GRK3NR4A2GRK5 | |
| SCHEMBL4748825 | 0.77 | CTSV (0.67) | FFAR1SRD5A2NR4A2NR1H4TSHR | |
| SCHEMBL5796419 | 0.77 | RAB9A (0.52) | GRK2GRK3GRK5SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |