Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | DGKA | P23743 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 4/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.43 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.43 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1695888 | 1.00 | KDM4E (0.63) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL30099173 | 1.00 | KDM4E (0.63) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL28762308 | 1.00 | KDM4E (0.63) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL30923587 | 1.00 | KDM4E (0.63) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL1703996 | 0.98 | KDM4E (0.60) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL483603 | 0.98 | KDM4E (0.60) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Glyceryl Monostearate SCHEMBL16694502 | 0.95 | KDM4E (0.74) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL29791959 | 0.95 | KDM4E (0.74) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Myristic Acid SCHEMBL8885381 | 0.95 | KDM4E (0.74) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Stearic Acid SCHEMBL30063427 | 0.95 | KDM4E (0.74) | KDM4EDUSP3MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2887929-A2 | COMPOUNDS FOR PREVENTING, REDUCING AND/OR ALLEVIATING ITCHY SKIN CONDITION(S) | Symrise AG (DE) | 2015-07-01 | — | — | EP | claimed |
| WO-2012143576-A2 | COMPOUNDS FOR PREVENTING, REDUCING AND/OR ALLEVIATING ITCHY SKIN CONDITION(S) | SYMRISE AG (DE) | 2012-10-26 | — | — | WO | claimed |
| EP-2416766-A2 | COMPOSITIONS COMPRISING TRANS-TERT-BUTYL CYCLOHEXANOL AS SKIN IRRITATION-REDUCING AGENT | Symrise AG (DE) | 2012-02-15 | — | — | EP | claimed |
| WO-2009087242-A2 | COMPOSITIONS COMPRISING TRANS-TERT-BUTYL CYCLOHEXANOL AS SKIN IRRITATION-REDUCING AGENT | SYMRISE GMBH & CO. KG (DE) | 2009-07-16 | — | — | WO | claimed |
| EP-4373462-A1 | COMPOSITIONS OF DICAFFEOYLQUINIC ACIDS WITH TOCOPHEROL | Symrise AG (DE) | 2024-05-29 | — | — | EP | disclosed |
| EP-3344220-B1 | MICROCAPSULES ENCAPSULATING A REFLECTIVE AGENT | TAGRA BIOTECHNOLOGIES LTD (IL) | 2024-05-08 | — | — | EP | disclosed |
| CN-117651544-A | Synergistic effect of dicaffeoylquinic acid and tocopherol | 西姆莱斯有限公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-117481998-A | Retinol substitutes in skin treatment | 西姆莱斯有限公司 | 2024-02-02 | — | — | CN | disclosed |
| US-11801210-B2 | Retinol replacement in skin treatment | SYMRISE AG (DE) | 2023-10-31 | — | — | US | disclosed |
| CN-116546961-A | Composition for product protection comprising (bio) -alkanediol and antimicrobial agent | 西姆莱斯股份公司 | 2023-08-04 | — | — | CN | disclosed |
| US-11696884-B2 | Compositions comprising menthol compounds as smoothing agents | SYMRISE AG (DE) | 2023-07-11 | — | — | US | disclosed |
| WO-2023001385-A1 | COMPOSITIONS OF DICAFFEOYLQUINIC ACIDS WITH TOCOPHEROL | SYMRISE AG (DE) | 2023-01-26 | — | — | WO | disclosed |
| EP-2416766-A2 | COMPOSITIONS COMPRISING TRANS-TERT-BUTYL CYCLOHEXANOL AS SKIN IRRITATION-REDUCING AGENT | Symrise AG (DE) | 2012-02-15 | — | — | EP | disclosed |
| EP-2389922-A1 | Cyclohexyl carbamate compounds as anti-ageing actives | Symrise AG (DE) | 2011-11-30 | — | — | EP | disclosed |
| WO-2010122178-A2 | CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE GMBH & CO. KG (DE) | 2010-10-28 | — | — | WO | disclosed |
| WO-2010097479-A2 | CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS | SYMRISE GMBH & CO. KG (DE) | 2010-09-02 | — | — | WO | disclosed |
| WO-2010097480-A2 | MENTHYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE GMBH & CO. KG (DE) | 2010-09-02 | — | — | WO | disclosed |
| WO-2010089421-A2 | MENTHYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS | SYMRISE GMBH & CO. KG (DE) | 2010-08-12 | — | — | WO | disclosed |
| WO-2009087242-A2 | COMPOSITIONS COMPRISING TRANS-TERT-BUTYL CYCLOHEXANOL AS SKIN IRRITATION-REDUCING AGENT | SYMRISE GMBH & CO. KG (DE) | 2009-07-16 | — | — | WO | disclosed |
| US-20080318900-A1 | Cosmetic Compositions Comprising At Least One Bis-Urea Derivative | L'OREAL S.A. (FR) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11696884-B2 | Compositions comprising menthol compounds as smoothing agents | SMURF1, SMURF2, S1PR2 | KDM4E 498/4885DUSP3 3224/4885MEN1 1225/4885 |
| US-11801210-B2 | Retinol replacement in skin treatment | RBP1, RBP4, LRAT | KDM4E 2857/4885DUSP3 4454/4885MEN1 3632/4885 |
| US-20080318900-A1 | Cosmetic Compositions Comprising At Least One Bis-Urea Derivative | KRT18, DEGS1, DSG1 | KDM4E 1298/4885DUSP3 2770/4885MEN1 2138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.