Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | DGKA | P23743 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483603 | 1.00 | KDM4E (0.60) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL30099173 | 0.98 | KDM4E (0.63) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL30923587 | 0.98 | KDM4E (0.63) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL1695888 | 0.98 | KDM4E (0.63) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL28762308 | 0.98 | KDM4E (0.63) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL579964 | 0.98 | KDM4E (0.63) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL609590 | 0.94 | KDM4E (0.68) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Stearic Acid SCHEMBL30063427 | 0.93 | KDM4E (0.74) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Myristic Acid SCHEMBL8885381 | 0.93 | KDM4E (0.74) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL29791959 | 0.93 | KDM4E (0.74) | KDM4EDUSP3MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492514-B1 | NOVEL SILICONE COMPOUND AND COSMETIC CONTAINING SAME | SHINETSU CHEMICAL CO (JP) | 2023-05-10 | — | — | EP | disclosed |
| US-10787544-B2 | Silicone compound and cosmetic containing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-09-29 | — | — | US | disclosed |
| US-20190211156-A1 | NOVEL SILICONE COMPOUND AND COSMETIC CONTAINING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2019-07-11 | — | — | US | disclosed |
| EP-3492514-A1 | NOVEL SILICONE COMPOUND AND COSMETIC CONTAINING SAME | Shin-Etsu Chemical Co., Ltd. (JP) | 2019-06-05 | — | — | EP | disclosed |
| US-9890252-B2 | Silicone compound and cosmetic containing thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-02-13 | — | — | US | disclosed |
| EP-3168255-B1 | NOVEL SILICONE COMPOUND AND COSMETIC CONTAINING THEREOF | SHINETSU CHEMICAL CO (JP) | 2018-01-31 | — | — | EP | disclosed |
| EP-2641929-B1 | NOVEL ORGANOPOLYSILOXANE, COSMETIC CONTAINING THEREOF, AND METHOD FOR PREPARING ORGANOPOLYSILOXANE | SHINETSU CHEMICAL CO (JP) | 2017-11-29 | — | — | EP | disclosed |
| EP-2662400-B1 | Block type-modified organopolysiloxane, method for using the organopolysiloxane, cosmetic, and method for producing the organopolysiloxane | SHINETSU CHEMICAL CO (JP) | 2017-09-13 | — | — | EP | disclosed |
| CN-103356403-B | Cosmetic | 信越化学工业株式会社 | 2017-07-28 | — | — | CN | disclosed |
| US-20170137574-A1 | NOVEL SILICONE COMPOUND AND COSMETIC CONTAINING THEREOF | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-05-18 | — | — | US | disclosed |
| EP-2641929-A2 | Novel organopolysiloxane, cosmetic containing thereof, and method for preparing organopolysiloxane | Shin-Etsu Chemical Co., Ltd. (JP) | 2013-09-25 | — | — | EP | disclosed |
| EP-2581401-A1 | Glycerol group-containing organopolysiloxane, cosmetic, and method for producing glycerol group-containing organopolysiloxane | Shin-Etsu Chemical Co., Ltd. (JP) | 2013-04-17 | — | — | EP | disclosed |
| US-20130089509-A1 | GLYCEROL GROUP-CONTAINING ORGANOPOLYSILOXANE, COSMETIC, AND METHOD FOR PRODUCING GLYCEROL GROUP-CONTAINING ORGANOPOLYSILOXANE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-04-11 | — | — | US | disclosed |
| EP-2030966-B1 | BENZYLIDENE MALONAMIDE AND SALT THEREOF, ULTRAVIOLET RAY ABSORBENT, AND AGENT FOR EXTERNAL APPLICATION TO THE SKIN | SHISEIDO CO LTD (JP) | 2013-01-02 | — | — | EP | disclosed |
| US-20120093746-A1 | AMINO ACID-MODIFIED ORGANOPOLYSILOXANE, MAKING METHOD, AND COSMETICS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-04-19 | — | — | US | disclosed |
| EP-2441790-A1 | Amino acid-modified organopolysiloxane, making method, and cosmetics | Shin-Etsu Chemical Co., Ltd. (JP) | 2012-04-18 | — | — | EP | disclosed |
| US-8003083-B2 | Benzylidene malonamide and salt thereof, ultraviolet ray absorbent, and agent for external application to the skin | SHISEIDO COMPANY, LTD. (JP) | 2011-08-23 | — | — | US | disclosed |
| US-20100254921-A1 | Benzylidene Malonamide And Salt Thereof, Ultraviolet Ray Absorbent, And Agent For External Application To The Skin | SHISEIDO COMPANY, LTD. (JP) | 2010-10-07 | — | — | US | disclosed |
| EP-2030966-A1 | BENZYLIDENE MALONAMIDE AND SALT THEREOF, ULTRAVIOLET RAY ABSORBENT, AND AGENT FOR EXTERNAL APPLICATION TO THE SKIN | SHISEIDO COMPANY, LTD. (JP) | 2009-03-04 | — | — | EP | disclosed |
| EP-1095959-A2 | Cosmetic composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137574-A1 | NOVEL SILICONE COMPOUND AND COSMETIC CONTAINING THEREOF | CCND2, MRGPRX1, MRGPRX2 | KDM4E 1256/4885DUSP3 4803/4885MEN1 1135/4885 |
| US-20120093746-A1 | AMINO ACID-MODIFIED ORGANOPOLYSILOXANE, MAKING METHOD, AND COSMETICS | DAO, AADAT, BCAT2 | KDM4E 1444/4885DUSP3 4857/4885MEN1 1823/4885 |
| US-20100254921-A1 | Benzylidene Malonamide And Salt Thereof, Ultraviolet Ray Absorbent, And Agent For External Application To The Skin | UROD, MAL2, SI | KDM4E 115/4885DUSP3 3972/4885MEN1 692/4885 |
| US-20190211156-A1 | NOVEL SILICONE COMPOUND AND COSMETIC CONTAINING THE SAME | CCND2, SRD5A1, DRD1 | KDM4E 1524/4885DUSP3 4879/4885MEN1 618/4885 |
| US-20130089509-A1 | GLYCEROL GROUP-CONTAINING ORGANOPOLYSILOXANE, COSMETIC, AND METHOD FOR PRODUCING GLYCEROL GROUP-CONTAINING ORGANOPOLYSILOXANE | GK, MGLL, MRGPRX2 | KDM4E 3234/4885DUSP3 4868/4885MEN1 2149/4885 |
| US-10787544-B2 | Silicone compound and cosmetic containing the same | FANCD2, CCND2, MRGPRX1 | KDM4E 1514/4885DUSP3 4874/4885MEN1 606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.