Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 10/20 | 0.39 |
| ▸ | TDO2 | P48775 | 4/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | CCKAR | P32238 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5795433 | 0.90 | IDO1 (0.40) | IDO1TDO2KDM4ENPC1RXFP1 | |
| SCHEMBL5795631 | 0.90 | MAPT (0.36) | IDO1TDO2EGFRKDM4ENPC1 | |
| SCHEMBL5797812 | 0.74 | DHODH (0.42) | DHODHKDM4ECYP2C9HPGDCYP2C19 | |
| SCHEMBL5796057 | 0.74 | CYP2C9 (0.40) | DHODHKDM4EATMCYP2C9HPGD | |
| SCHEMBL5797409 | 0.71 | HTT (0.40) | DHODHCYP2C9HPGDCYP2C19HTT | |
| SCHEMBL5796765 | 0.71 | MAPT (0.41) | DHODHKDM4ECYP2C9HPGDCYP2C19 | |
| SCHEMBL5799640 | 0.70 | MAPT (0.52) | DHODHKDM4EATMHTT | |
| SCHEMBL5799741 | 0.68 | ALDH1A1 (0.40) | DHODHKDM4ENPC1 | |
| SCHEMBL1302976 | 0.68 | EGFR (0.69) | IDO1TDO2EGFRKDM4EHPGD | |
| SCHEMBL5799654 | 0.67 | NPC1 (0.39) | DHODHKDM4ECYP2C9HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |