Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PER2 | O15055 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GRK2 | P25098 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799320 | 0.91 | HDAC1 (0.40) | HTTLMNAPER2NQO2 | |
| SCHEMBL5798794 | 0.90 | NQO2 (0.40) | HTTLMNASMN1; SMN2PER2HPGD | |
| SCHEMBL5796057 | 0.82 | CYP2C9 (0.40) | HTTSMN1; SMN2CYP2C9HPGDCYP2C19 | |
| SCHEMBL5797812 | 0.77 | DHODH (0.42) | HTTSMN1; SMN2CYP2C9HPGDCYP2C19 | |
| SCHEMBL5796765 | 0.74 | MAPT (0.41) | HTTSMN1; SMN2CYP2C9HPGDCYP2C19 | |
| SCHEMBL5799640 | 0.74 | MAPT (0.52) | HTTDHODHPOLBALDH1A1RCE1 | |
| SCHEMBL5796847 | 0.72 | HDAC6 (0.40) | HTTCYP2C9HPGDCYP2C19 | |
| SCHEMBL5799741 | 0.72 | ALDH1A1 (0.40) | LMNASMN1; SMN2DHODHALDH1A1MAPK1 | |
| SCHEMBL5799669 | 0.71 | IDO1 (0.39) | HTTCYP2C9HPGDCYP2C19DHODH | |
| SCHEMBL5813399 | 0.71 | P2RX3 (0.49) | HTTLMNASMN1; SMN2CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |