Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821639 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1HPGDHDAC1HDAC6 | |
| SCHEMBL5795629 | 0.86 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1HPGDHTTMAPT | |
| SCHEMBL5799786 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1HPGDHTTMAPT | |
| SCHEMBL5821122 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL5795985 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL1306293 | 0.76 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL1306294 | 0.76 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1HTTMEN1KMT2A | |
| Benzoic Acid SCHEMBL5808846 | 0.72 | TSHR (0.43) | SMN1; SMN2ALDH1A1HPGDHDAC1HDAC6 | |
| SCHEMBL22042582 | 0.71 | RAB9A (0.57) | SMN1; SMN2ALDH1A1HPGDHDAC1HDAC6 | |
| SCHEMBL5822229 | 0.70 | MAPT (0.51) | SMN1; SMN2ALDH1A1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |