Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800961 | 0.98 | LMNA (0.40) | LMNAKMT2AAKR1C3AKR1C2PIK3CD | |
| SCHEMBL5797942 | 0.89 | PTGS2 (0.43) | PTGS2KDM4EELANECYP19A1ALDH1A1 | |
| SCHEMBL5801055 | 0.87 | PTGS2 (0.41) | PTGS2ELANE | |
| SCHEMBL5800291 | 0.86 | LMNA (0.39) | LMNAKMT2AAKR1C3AKR1C2PIK3CD | |
| SCHEMBL5797220 | 0.86 | PTGS2 (0.40) | KMT2AAKR1C3AKR1C2PTGS2MEN1 | |
| SCHEMBL5797992 | 0.86 | LMNA (0.39) | LMNAKMT2AAKR1C3AKR1C2PIK3CD | |
| SCHEMBL5820041 | 0.86 | PTGS2 (0.42) | AKR1C3AKR1C2PTGS2KDM4ECYP19A1 | |
| SCHEMBL5797827 | 0.85 | LMNA (0.47) | LMNAKMT2AAKR1C3AKR1C2PTGS2 | |
| SCHEMBL5814641 | 0.85 | AKR1C3 (0.41) | LMNAAKR1C3AKR1C2PIK3CDPTGS2 | |
| SCHEMBL5797826 | 0.85 | LMNA (0.47) | LMNAKMT2AAKR1C3AKR1C2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |