Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5822711 | 0.98 | LMNA (0.39) | LMNAKMT2APIK3CDALDH1A1MEN1 | |
| SCHEMBL5800993 | 0.91 | PTGS2 (0.37) | ALDH1A1KDM4ECYP19A1HSD11B1CHRNB2 | |
| SCHEMBL5819926 | 0.90 | L3MBTL1 (0.37) | ALDH1A1HSD11B1CHRNB2SLC6A2CHRNB4 | |
| SCHEMBL5797664 | 0.89 | LMNA (0.38) | LMNAKMT2APIK3CDALDH1A1MEN1 | |
| SCHEMBL5560260 | 0.89 | PTGS2 (0.37) | KMT2AALDH1A1MEN1CYP19A1HSD11B1 | |
| SCHEMBL5800554 | 0.87 | PTGS2 (0.38) | KMT2AALDH1A1AKR1C3AKR1C2CYP19A1 | |
| SCHEMBL5554521 | 0.87 | LMNA (0.38) | LMNAKMT2APIK3CDALDH1A1MEN1 | |
| SCHEMBL5558388 | 0.87 | PTGS2 (0.35) | KMT2AALDH1A1MEN1AKR1C3AKR1C2 | |
| SCHEMBL5819680 | 0.86 | PTGS2 (0.37) | AKR1C3AKR1C2CYP19A1 | |
| SCHEMBL5798701 | 0.86 | PTGS2 (0.45) | AKR1C3AKR1C2SMN1; SMN2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |