Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 4/20 | 0.42 |
| ▸ | SNCA | P37840 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5474617 | 0.77 | ALDH1A1 (0.61) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL5481632 | 0.73 | P2RX4 (0.52) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9453625 | 0.72 | KMT2A (0.54) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL11556531 | 0.72 | MAPK1 (0.69) | MAPTALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL16880622 | 0.70 | P2RX4 (0.52) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL5484204 | 0.70 | SMN1; SMN2 (0.48) | MAPTALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL5800407 | 0.69 | KMT2A (0.44) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL5480233 | 0.68 | HTR6 (0.43) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL23296136 | 0.68 | DBH (0.54) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL16339690 | 0.67 | JAK2 (0.54) | MAPTLMNANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010529-A1 | Nitrogenous heterocyclic compounds and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010529-A1 | Nitrogenous heterocyclic compounds and medical use thereof | MAPK1, NOS1, NOS2 | MAPT 1199/4885ALDH1A1 1694/4885LMNA 2404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.