Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5822466 | 0.85 | PIM1 (0.41) | TAAR1RAB9ASMN1; SMN2NPC1TSHR | |
| SCHEMBL434201 | 0.72 | ASIC3 (0.44) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL207607 | 0.71 | CALM1 (0.55) | CALM1TSHRHPGDALDH1A1 | |
| SCHEMBL17697662 | 0.69 | CALM1 (0.42) | CALM1TAAR1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL818602 | 0.67 | CALM1 (0.44) | CALM1TAAR1CYP11B1CYP11B2TSHR | |
| SCHEMBL559143 | 0.66 | MTOR (0.39) | TAAR1CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL8830170 | 0.66 | LTA4H (0.44) | CYP11B1CYP11B2RAB9ASMN1; SMN2NPC1 | |
| Diphenylmethane SCHEMBL10336493 | 0.65 | CALM1 (0.80) | CALM1TAAR1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10629127 | 0.63 | CALM1 (0.50) | CALM1TAAR1TSHRALDH1A1LMNA | |
| SCHEMBL2091627 | 0.63 | CALM1 (0.57) | CALM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006033995-A2 | THIAZOLIDIN-4-ONES HAVING ANTI-HEPATITIS B ACTIVITY | VALEANT RESEARCH AND DEVELOPMENT (US) | 2006-03-30 | — | — | WO | disclosed |