Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970779 | 0.81 | NR1H4 (0.49) | MEN1KMT2ASMN1; SMN2CASRRAB9A | |
| SCHEMBL5799643 | 0.80 | BRAF (0.49) | CSF1RCYP2C9 | |
| SCHEMBL2859259 | 0.79 | SLC7A5 (0.60) | MEN1KMT2ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL4966996 | 0.77 | ROCK2 (0.44) | MEN1KMT2ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL4749868 | 0.77 | BRAF (0.67) | CSF1RCYP2C9 | |
| SCHEMBL3929589 | 0.76 | BRAF (0.63) | MEN1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL4750556 | 0.76 | BRAF (0.67) | CSF1RCYP2C9 | |
| SCHEMBL4750077 | 0.74 | BRAF (0.57) | CYP2C9 | |
| SCHEMBL5212609 | 0.74 | MAPT (0.52) | MEN1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL5803018 | 0.73 | BRAF (0.54) | CSF1RCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006067445-A2 | CSF-1R KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | disclosed |